Consider all causes and actions, and then act in the way that brings about the greatest positive impact.
Apply evidence, science and reason to determine the most effective ways to improve the world.
Value all sentient life, regardless of nationality, creed, ancestry, religion, or species
Will progress on the cause drastically improve a large number of lives?
Can a dedicated effort in support of the cause create a measurable difference?
How much has the cause been overlooked or undervalued?